Active Ingredients: Azithromycin
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Although the study did support the potential use of azithromycin as a prophylaxis against malaria, the subjects were partially immune residents.
Obviously, larger trials with nonimmune individuals would be needed to assess its efficacy in travelers. For now, azithromycin appears to be a possible future alternative for malaria prophylaxis, but more work needs to be done.
Am J Trop Med Hyg 1983. Am J Trop Med Hyg 1993; 49 1:101-105. Kuschner RA, et al. Lancet 1994.
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Sadiq ST, et al. Women tend to have longer QT intervals and higher risk of TdP than men largely because of the effects of sex hormones on myocardial tissue. It is reported that Ray et al.
This overestimation largely contributed to the significant association observed between azithromycin use and cardiac deaths. Third, it is also possible that azithromycin and levofloxacin affect adversely on the cardiovascular profile.This prescription required excellent leadership, and having taken a mirror from a box of carved cedarwood, all Without nutrients and calories they require to sustain Get can be obtained from 1000 sources.
This can only be observed in patients with risk factors of QT prolongation, such as the use of QT-prolonging medications. Although prolonged QT interval is not a strong indicator for predicting the TdP and adverse cardiac events, the data from the clinical trials are still valuable in understanding the cardiac safety of azithromycin and levofloxacin.
However, the current studies evaluating the cardiac safety profile of azithromycin and levofloxacin are imperfect for drawing a firm conclusion in both individual and population levels. Considering the wide use of azithromycin and levofloxacin in infectious diseases, there is a greater need for further examination of their cardiovascular safeties, particularly for patients with common infections, such as community-acquired pneumonia.