Active Ingredients: Azithromycin
All patients with sexually transmitted urethritis or cervicitis should have a serologic test for syphilis and appropriate cultures for gonorrhea performed at the time of diagnosis.
Appropriate antibacterial therapy and follow-up tests for these diseases should be initiated if infection is confirmed. Development of Drug-Resistant Bacteria Prescribing Zithromax in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
In clinical trials, most of the reported adverse reactions were mild to moderate in severity and were reversible upon discontinuation of the drug.
Approximately 0. Serious adverse reactions included angioedema and cholestatic jaundice.
Most of the adverse reactions leading to discontinuation were related to the gastrointestinal tract. Gastrointestinal: Dyspepsia, flatulence, vomiting, melena, and cholestatic jaundice.
Genitourinary: Monilia, vaginitis, and nephritis. Nervous System: Dizziness, headache, vertigo, and somnolence. General: Fatigue.
Allergic: Rash, photosensitivity, and angioedema. Chronic therapy with 1200 mg weekly regimen The nature of adverse reactions seen with the 1200 mg weekly dosing regimen for the prevention of Mycobacterium avium infection in severely immunocompromised HIV-infected patients were similar to those seen with short-term dosing regimens.
Five percent of patients experienced reversible hearing impairment in the pivotal clinical trial for the treatment of disseminated MAC in patients with AIDS.
Hearing impairment has been reported with macrolide antibiotics, especially at higher doses.
Discontinuations from treatment due to laboratory abnormalities or adverse reactions considered related to study drug occurred in 8 of 88 9.
Single 1 gram dose regimen Overall, the most common adverse reactions in patients receiving a single-dose regimen of 1 gram of Zithromax were related to the gastrointestinal system and were more frequently reported than in patients receiving the multiple-dose regimen.
Postmarketing Experience The following adverse reactions have been identified during post approval use of azithromycin. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.It is used if the mucus No Prescription Required infected with bacteria because of the caused by chlamydia.