Active Ingredients: Orlistat
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Like anything else, civilization tightening skin weight loss is valuable. In conclusion, even if orlistat is scarcely absorbed by oral route, it is possible that this drug could reduce local MGMT-mediated protection against DNA damage provoked by DNA methylating compounds on gastrointestinal tract epithelial cells, thus favoring chemical carcinogenesis.
Introduction Tetrahydrolipstatin orlistat, a well-known irreversible inhibitor of pancreatic and gastric lipases, is extensively used as anti-obesity drug 1.
Of particular interest is the finding that orlistat is also a potent inhibitor of fatty acid synthase FASN, an enzyme that plays an important role in tumor growth and progression 2 and is considered a metabolic oncogene 3.