Active Ingredients: Ivermectin
Ivermectin is effective in killing some, but not all, of these parasites. While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly contraindicated.
Clinical Place for the Proposed Therapy Scabies is a parasitic infestation of the skin caused by the mite Sarcoptes scabiei, var hominis, a human pathogen, which is spread by close physical contact between infected persons.
Whilst the majority of patients suffer from typical scabies, some patients develop crusted scabies, a severe form of scabies characterised by crusted lesions affecting the palms and soles, and thickened and dystrophic nails.
Scabies infestation can lead to pyoderma, skin sores infested with bacteria, especially group A streptococcus or Staphylococcus aureus. For crusted scabies, ivermectin plus topical treatment including PBS listed permethrin is proposed as first line treatment of crusted scabies.
Ivermectin is proposed for the treatment of patients who have failed topical therapy. The PBAC considered that ivermectin in conjunction with topical treatment is currently the only effective treatment for crusted scabies, while the appropriate clinical place of ivermectin for the treatment of typical scabies in practice was after the failure of permethrin and benzyl benzoate.
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