Active Ingredients: Ivermectin
Since then, the efficacy of ivermectin has been confirmed in 3 larger studies. Table 3 Treatment of cutaneous larva migrans with a single oral 12-mg dose of ivermectin.
Table 3 Open in new tab Download slide Treatment of cutaneous larva migrans with a single oral 12-mg dose of ivermectin. Another study involved 67 Belgian tourists treated with a single dose 12 mg of ivermectin.
The median intervals until disappearance of the pruritus and lesions were 3 days range, 1—7 days for the patients who received a second dose, and 9 days range, 4—30 days for those who received a third dose.
Only 2 patients were not cured by ivermectin.
Ivermectin has been well tolerated in studies of patients with cutaneous larva migrans, and no adverse effects have been reported in indications other than filariasis. Almost all the adverse effects are a result of the patient's immune response to killed microfilariae.
An open study compared the efficacy of single doses of oral ivermectin 12 mg and oral albendazole 400 mg in the treatment of cutaneous larva migrans.
No major adverse effects were observed. The investigators concluded that a single 12-mg dose of ivermectin was more effective than a single 400-mg dose of albendazole for the treatment of cutaneous larva migrans.
Prevention Because tourists are usually infected by walking or lying on tropical sandy beaches contaminated by dog feces, the best way to prevent cutaneous larva migrans is to ban dogs from beaches figure 2, top.
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It is effective against a wide range of parasites, including gastrointestinal roundworms, lungworms, mites, lice and hornflies.