Active Ingredients: Norfloxacin
Steady-state concentrations of norfloxacin will be attained within two days of dosing. Norfloxacin is least soluble at urinary pH of 7.
Other companies initiated fluoroquinolone discovery programs in the aftermath of the publication of the norfloxacin patent.
Bayer Pharmaceuticals discovered that the addition of a single carbon atom to the norfloxacin structure provided another 4 to 10-fold improvement in activity.
The U. Among the 95 patients treated, 76 80 percent were considered to have had a cure and five 5 percent showed improvement. This is to prevent the infection from coming back.
If you have a long-term chronic infection, your course of treatment will be for longer than this, possibly for 1-3 months. If you still feel unwell after finishing the course of tablets, go back to see your doctor.
Getting the most from your treatment Remember to keep any routine appointments with your doctor. This is so your progress can be monitored.
Protect your skin by using a sunscreen, particularly if you are exposed to strong sunlight for a prolonged period of time. Do not use sunbeds.
If you buy any medicines check with a pharmacist that they are safe to take with this antibiotic. In particular, do not take painkillers called non-steroidal anti-inflammatory drugs NSAIDs, such as ibuprofen, while you are taking norfloxacin.
The manufacturer only recommends use of norfloxacin during pregnancy when benefit outweighs risk. Ciprofloxacin is being licensed for the treatment of Complicated Urinary Tract Infections and Pyelonephritis due to Escherichia coli and Inhalational Anthrax post-exposure and levofloxacin was recently licensed for the treatment of Inhalational Anthrax post-exposure.
However, the Fluoroquinolones are licensed to treat lower respiratory infections in children with cystic fibrosis in the UK. Adverse effects In general, fluoroquinolones are well tolerated, with most side-effects being mild to moderate.
The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients treated with other antibiotic classes.Medical uses The initial approval by the U. It licensed use in acute and chronic complicated kidney infections has been.
If you have a condition causing tired and weak muscles, called myasthenia gravis. This is a genetic disorder which causes problems after eating foods such as fava beans.