Active Ingredients: Norfloxacin
Contraindications As noted above, under licensed use, norfloxacin is also now considered to be contraindicated for the treatment of certain sexually transmitted diseases by some experts due to bacterial resistance.
Patients taking any of these drugs concomitantly with norfloxacin should be carefully monitored.
Pregnancy Norfloxacin has been reported to rapidly cross the blood-placenta and blood-milk barrier, and is extensively distributed into the fetal tissues.
For this reason norfloxacin and other fluoroquinolones are contraindicated during pregnancy due to the risk of spontaneous abortions and birth defects.
The manufacturer only recommends use of norfloxacin during pregnancy when benefit outweighs risk. Ciprofloxacin is being licensed for the treatment of Complicated Urinary Tract Infections and Pyelonephritis due to Escherichia coli and Inhalational Anthrax post-exposure and levofloxacin was recently licensed for the treatment of Inhalational Anthrax post-exposure.
However, the Fluoroquinolones are licensed to treat lower respiratory infections in children with cystic fibrosis in the UK.
Adverse effects In general, fluoroquinolones are well tolerated, with most side-effects being mild to moderate. In particular, do not take painkillers called non-steroidal anti-inflammatory drugs NSAIDs, such as ibuprofen, while you are taking norfloxacin.
Some people develop thrush redness and itching in the mouth or vagina after taking a course of antibiotics.
If you think you have thrush, speak with your doctor or pharmacist for advice. If you are having any vaccinations, make sure the person treating you knows that you are taking this medicine. Make sure your reactions are normal before you drive, operate machinery or do any other jobs which could be dangerous if you are not sufficiently alert.
Can norfloxacin cause problems? Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them.
The table below contains some of the most common ones associated with norfloxacin. You will find a full list in the manufacturer's information leaflet supplied with your medicine.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common norfloxacin side-effects What can I do if I experience this? Feeling sick nausea or being sick vomiting, indigestion, tummy abdominal pain Stick to simple foods - avoid rich or spicy meals Diarrhoea Drink plenty of water to replace lost fluids.Do not pass it on to.
If the diarrhoea is severe or continues to be a problem, speak with your pharmacist or doctor for advice Headache Drink plenty of water and ask your pharmacist to recommend a suitable painkiller.
If the headaches continue, let your doctor know Feeling dizzy Do not drive and do not use tools or machines until you feel well again Rash If this is severe, let your doctor know Important: there are also a number of less common but more serious side-effects which have been associated with norfloxacin.
You should check with your doctor or pharmacist if you are not sure. The usual dose in adults is 1 film-coated tablet 400 mg norfloxacin twice daily. The recommended dose is 1 film-coated tablet 400 mg norfloxacin once daily.