Active Ingredients: Norfloxacin
The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients treated with other antibiotic classes.
Centers for Disease Control study found patients treated with fluoroquinolones experienced adverse events severe enough to lead to an emergency department visit more frequently than those treated with cephalosporins or macrolides, but less frequently than those treated with penicillins, clindamycin, sulfonamides, or vancomycin.
Among these, tendon problems and exacerbation of the symptoms of the neurological disorder myasthenia gravis are the subject of "black box" warnings in the United States.
Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients. Simultaneous use of corticosteroids is present in almost one-third of quinolone-associated tendon rupture.
Fluoroquinoline treatment is associated with risk that is similar to or less than that associated with broad spectrum cephalosporins.
Therefore, cyclosporine serum levels should be monitored and appropriate cyclosporine dosage adjustments made when these drugs are used concomitantly.
Medications Some quinolones exert an inhibitory effect on the cytochrome P-450 system, thereby reducing theophylline clearance and increasing theophylline blood levels.
Additionally other fluoroquinolones, especially enoxacin, and to a lesser extent ciprofloxacin and pefloxacin, also inhibit the metabolic clearance of theophylline. As such, these drug interactions involving the fluoroquinolones appear to be drug specific rather than a class effect.
The fluoroquinolones have also been shown to interfere with the metabolism of caffeine and the absorption of levothyroxine.
Continue taking your medicine regularly as prescribed. If you have taken more than a double dose by mistake, contact your doctor immediately.
If you forget to take Norfloxacin 400 mg Do not take a double dose to make up for a forgotten tablet, just carry on with the next one as normal.
If you stop taking Norfloxacin 400 mg It is important that you complete the course of treatment, even if you begin to feel better after a few days. If you have any further questions on the use of this product, ask your doctor or pharmacist or nurse.
Like all medicines, this medicine can cause side effects, although not everybody gets them. Allergic reactions can, very rarely, be life-threatening.
Achilles tendon. Inflammation of the liver with jaundice yellowing of the skin or whites of the eyes commonly occurs.
Stop treatment and contact your doctor if you experience signs and symptoms of liver problems such as loss of appetite, jaundice, dark urine, itching or sensitivity to pressure in the abdominal cavity.It was whilst on my own of conditions that effect interaction, communication, interests and behaviour, including Asperger syndrome and childhood autism.
If you develop the rare side effect of severe and persistent diarrhoea whilst you are taking your tablets or after stopping your tablets you should consult your doctor.
In rare cases seizures occur. If fits occur, stop taking this medicine.