Active Ingredients: Gabapentin
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The primary end point was the time-matched difference in individualized baseline-adjusted QTc ddQTcIb between gabapentin enacarbil and placebo.
General tolerability was also monitored. The mobile phase consisted of 0. Samples were eluted at a flow rate of 1.
The detection was carried out at 210 nm. The calibration curve was constructed and analyzed before each sample to ensure reproducibility of the analysis.
Samples from fresh and stored gabapentin suspensions were diluted with deionized water, filtered using 0. Spectral scanning was conducted to fresh samples weighing approxi- mately 4 mg as KBr discs from 4000 to 400 cm—1 at a resolution of 4 cm—1.