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    We have previously published comparisons of testosterone to placebo effects on sexual function Spitzer et al. This report char-acterizes the hormonal changes among participants after initiating sildenafil monotherapy, prior to randomization. Sildenafil dose optimization Participants were each started and optimized on sildenafil for 3—7 weeks during the open-label phase.

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    Men were generally started on sildenafil 50 mg p. Those reporting prior use of sildenafil 100 mg daily were started on this dose. Men receiving 25 or 50 mg had an opportunity to increase this dose up to 100 mg p.

    Free testosterone was calculated from total testosterone and SHBG using the law of mass action Vermeulen et al.

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    Interassay coefficients of variation for oestradiol were 9. The interassay coefficients of variation for oestrone were 8. LH and follicle-stimulating hormone FSH were assessed using fluoroimmunoassays PerkinElmer, each with a sensitivity of 0.

    The interassay coefficients of variation for the LH assay were 3. The interassay coefficients of variation for the FSH assay were 1.

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    Interassay coefficients of variation for androstene-dione are 9. One more important point: adding testosterone to sildenafil Viagra treatment has no added benefit in men with erectile dysfunction and low testosterone levels, as noted in one well-designed clinical study.

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    However, some men still prefer the brand names. But beware. Know that these prices can vary based on the pharmacy, your location, and if you use an online pharmacy coupon.

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