Active Ingredients: Hydroxyzine
This study also found that RLS had a significant impact on the health of these patients as their Short Form-36 SF-36 scores were significantly below population norms, matching those of patients with other chronic medical conditions, such as diabetes and clinical depression.
As demonstrated by several other studies, this study confirmed that RLS was twice as common in women compared to men and the prevalence increases up to 80 years old after which it decreases. Secondary RLS is most often associated with iron deficiency, pregnancy and end-stage renal failure.
Similar to the approach for patients with back pain, therapeutic decisions should be based on the frequency and severity of symptoms and the disability that results from them.
Alerting Activities Symptoms characteristically occur when patients are at rest both physically and mentally. Although the preferred activity to relieve symptoms is physical movement walking, moving the affected limb, massage, and so forth, it is not always possible e.
However, patients report that passive activities, such as watching the in-flight movie provide no relief.
Abstinence from Caffeine, Nicotine, and Alcohol There is very little evidence in the medical literature supporting worsening of RLS by caffeine and improvement with cessation of its intake.
Furthermore, in clinical practice, an adverse response to caffeine is not very commonly seen.
The evidence supporting this negative association is based on 1 study performed in 1978 before the diagnostic criteria for diagnosing RLS was established, in which patients had complete remission of their RLS symptoms after stopping their caffeine intake.
This unblinded study had several flaws and has never been replicated. No significant differences in the incidence of RLS was found in a 1997 epidemiological study between Canadian adult smokers and nonsmokers, whereas 2 other epidemiological studies 1 in and another in both found an increased risk of RLS in smokers.
However, in clinical practice, the effect of smoking on RLS has not been very noticeable.
Although based on clinical experience, alcohol consumption tends to exacerbate RLS much more than the 2 substances in this section; the only study to support this link is the epidemiological study, which used telephone interviews on 1803 Kentucky adults.
Alcohol is commonly used by RLS sufferers as an easily available hypnotic to help them get to sleep, but in addition to worsening their RLS symptoms, it also increases wakefulness in the second half of the night and leads to disturbed sleep, even with a single low dose resulting in increased sleep fragmentation and number of awakenings in nonalcohol dependent adults.
Most physicians have no knowledge of the long list of drugs that affect RLS and thus frequently prescribe them for RLS sufferers. It also acts as an antihistamine that reduces the natural chemical histamine in the body.I received my medication much quicker. The Atarax arrived within a week than I thought.
Histamine can produce symptoms of sneezing and runny nose, or hives on the skin. Atarax is used as a sedative to treat anxiety and tension. It is also used together with other medications given for anesthesia.
Atarax is also used to treat allergic skin reactions such as hives or contact dermatitis.
Before you take Atarax, tell your doctor if you have: epilepsy or other seizure disorder; asthma, emphysema, or other breathing problem; glaucoma; heart disease or high blood pressure; stomach ulcer, blockage in your stomach or intestines; thyroid disorder; enlarged prostate or problems with urination; liver disease; or kidney disease.
SSRIs paroxetine, citalopram, escitalopram, fluoxetine, sertraline, or fluvoxamine are generally well tolerated and first-line drugs recommended for patients who never had any drug treatment for anxiety disorders. The success rate of SSRIs is limited up to 61.
The success rate of TCAs is limited up to 57. Alternative second-line drugs are monoamine oxidase inhibitors, namely, phenelzine and tranylcypromine which have side effects such as increased appetite, weight gain, and low blood pressure.
Third-line drugs in treatment include benzodiazepines oxazepam, lorazepam, temazepam, alprazolam, clonazepam, and diazepam, anticonvulsants carbamazepine, valproate, lamotrigine, topiramate, and gabapentin, atypical antipsychotics, and antihistaminic agents.
Benzodiazepines which have lower success rate nowadays are least preferred since they cause physical dependence and withdrawal symptoms.
There remains uncertainty in deciding an appropriate duration of prescribing these medications.