Active Ingredients: Isotretinoin
Another pigmentation mechanism is the accumulation of the drug alone, and chemical peels, it's possible to have a serious allergic reaction anaphylaxis to isotretinoin capsules.
Therefore, in this study we aimed to investigate the effect of systemic isotretinoin therapy on mucociliary transport and nasal surface mucosa using the saccharine test ST and nasal cytology techniques. Patients and Methods A total of 30 patients with severe or moderate acne were enrolled in this study.Epub Dec 11. Cutan Ocul Toxicol.
The study group was selected from a group of men and non-pregnant women having therapeutic failure with topical remedies and tetracyclines. How isotretinoin affects healing of other tissues such as cartilage, bone, and muscle is equally important.
In addition, understanding how iso- tretinoin might interfere in anesthesia, coagulation disor- ders, and susceptibility to infection is crucial.
Studies about isotretinoin and surgery have generally described wound healing of skin incisions. Few papers have discussed healing of other tissues, but no works have focused on overall surgery safety.
In this scenario, it is key that plastic surgeons 1 understand how isotretinoin might lead to negative surgery outcomes and 2 decide on appropriate timing to operate on patients who use isotretinoin.
This study presents a review of isotretinoin and focuses on these two issues. Methods Eleven topics were considered relevant to our question.
They included general aspects of isotretinoin; isotretinoin pharmacokinetics; interference of isotretinoin in skin, car- tilage, bone, and skeletal muscle healing; and disturbances caused by isotretinoin in blood coagulation, liver function and hepatic metabolism of other drugs, kidney function, heart rhythm, and susceptibility to infection.
Table 1 summarizes the topics of interest. The search returned a total of 4344 articles. Filtering was based on title and abstract reading.
After that, articles considered pertinent to our clinical question were fully read.
Studies about laser procedures and chemical peels were excluded because they were not considered surgical pro- cedures of interest to our clinical question.
Acne will normally keep improving for up to 8 weeks after stopping treatment. Most people have clear skin after that time, but a few will need another round of treatment. Are there other acne treatments?