Active Ingredients: Isotretinoin
Epistaxis only seen in conventional group but in our study.
Elevated liver function test results, and increase in serum lipid profiles was mild, and usually returned to normal within 6-8 weeks, despite continuation of treatment.
The present study showed that low dose 20 mg daily isotretiinoin represents a well-tolerated and efficient alternative to the standard 0.
The only pitfall is it is longer than 10 months duration of treatment period. The low frequency of adverse side-effects in this study, suggest that most side effects of the drug, are dose dependent; and the most serious side effects of the drug can be reduced significantly by using lower doses.
Hence, we recommend this low dose therapy for treatment of moderate to severe scar prone acne. A large, prospective randomized comparative study is needed to establish the definitive response and tolerance of this protocol.
Footnotes Conflict of Interest: None declared.
Prevalence of facial acne vulgaris in late adolescence and in adults. Br Med J. Oral isotretinoin is as effective as a combination of oral isotretinoin and topical anti-acne agents in nodulocystic acne.
Indian J Dermatol Venereol Leprol. Cautions with other medicines Some medicines and isotretinoin capsules can interfere with each other, and make it more likely that you'll have side effects.
Important Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.
Common questions How do isotretinoin capsules work? Isotretinoin capsules are only for severe acne. Isotretinoin capsules help severe acne by reducing the amount of natural oil made by your skin so blocked pores are less likely.
The medicine also kills the bacteria that cause acne, and relieves redness and soreness.
How long does it take to work? How long will treatment last? A treatment course of isotretinoin capsules usually lasts for 16 to 24 weeks around 4 to 6 months. Acne will normally keep improving for up to 8 weeks after stopping treatment.